Molecular Weight: 1209.39. : 344423-98-9. Atorvastatin calcium salt trihydrate is a specific inhibitor of -Hydroxy -methylglutaryl-CoA (HMG-CoA) reductase. calcium salt (2:1) trihydrate. Note. Common Chemistry. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. Change to read: 105 100 0 Atorvastatin Calcium contains NLT 98.0% and NMT 115 100 0 102.0% of atorvastatin calcium (C 66H 68CaF 2N 4O 10), calcu- Diluent: N,N-dimethylformamide lated on the anhydrous . The third chemical name is also added for Atorvastatin Calcium. i. PubChem. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Atorvastatin (as calcium trihydrate) tablets. The Chemical information section is revised to delete the term "trihydrate" from the chemical name, and to add chemical information for the solvate form. Safety Information Pictograms GHS08 Use of atorvastatin calcium trihydrate Atorvastatin is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Buy Atorvastatin Calcium Trihydrate (EP) from Simson Pharma Limited at best competitive price. Reddy's Atorvastatin Calcium Trihydrate (Form 1) API is the outcome of the extensive expertise in R&D, IP, and Regulatory. This leaflet answers some of the more common questions about APO-Atorvastatin. Atorvastatin calcium is very slightly soluble in Technical inquiry about: 41-Y0001327 Atorvastatin calcium trihydrate CRS Please use instead the cart to request a quotation or an order If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. ATORVASTATIN CALCIUM TRIHYDRATE [WHO-DD] CI-981; LIPITOR; SORTIS; TORVAST; TOTALIP; Resources. This reference standard was officially withdrawn from monograph 04/2021:2191 on 01/04/2022 and replaced by Atorvastatin calcium Y0002315. More than 60% of patients with diabetes uncontrolled for LDLC were maintained on suboptimal atorvastatin therapy (mean final dose: 29.9 mg vs maximum of 80 mg ). Atorvastatin calcium salt trihydrate is a specific inhibitor of -Hydroxy -methylglutaryl-CoA (HMG-CoA) reductase. Atorvastatin Calcium Trihydrate tergolong ke dalam obat-obatan terapi yang digunakan untuk menurunkan kadar lemak di dalam darah. What is in this leaflet . i. NCI Thesaurus. We achieve this by making sure that all our facilities are operating efficiently and to the latest standards of quality, safety, and . Compare Product No. 344423-98-9 - SHZPNDRIDUBNMH-NIJVSVLQSA-L - Atorvastatin calcium trihydrate - Similar structures search, synonyms, formulas, resource links, and other chemical information. itching, unusual tiredness; or. The reference will however remain available for sale for a further 6 months . Catalog NO. Table 1: Atorvastatin calcium Tablet Strengths and Identifying Features Tablet Strength Identifying Features 10 mg of atorvastatin UNII availability . Atorvastatin calcium trihydrate | C66H74CaF2N4O13 | CID 656846 - structure, chemical names, physical and chemical properties, classification, patents, literature . Atorvastatin calcium trihydrate. Reluctance to intensify therapy to attain accepted targets in highrisk individuals suggests a degree of clinical inertia not explained by objective evidence of dosedependent. Get medical attention. Catalogue Code: Y0001327 Name: Atorvastatin calcium trihydrate CRS . : 344423-98-9 | CAS NO. 3H 2 O. CAS Number: 344423-98-9. Simson Pharma provides best quality Atorvastatin Calcium Trihydrate (EP). Molecular Weight: 1209.39. : 344423-98-9. by JGK Mon Mar 14, 2011 7:37 pm. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia. Atorvastatin calcium trihydrate 344423-98-9 >95 Atorvastatin calcium 134523-03-8 - 4. This name employs the same naming convention as the names for specified impurities and Reference Standards listed in the monograph. Atorvastatine calcium trihydrate is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Buy Working Standards from Simson Pharma Limited, Every compound produced by Simson Pharma is accompanied by Certificate of Analysis. Obat ini masuk ke dalam golongan obat statin yang berperan dalam menurunkan kadar kolesterol yang tidak normal serta level lemak dalam darah. 3H 2 O. CAS No. Description SDS Pricing; Y0001327: European Pharmacopoeia (EP) Reference Standard: UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. Atorvastatin calcium trihydrate View Synonyms View Structure: Description: A pyrrole and heptanoic acid derivative,HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITOR (statin), and ANTICHOLESTEREMIC AGENT that is used to reduce serum levels of LDL-CHOLESTEROL; APOLIPOPROTEIN B; AND TRIGLYCERIDES and to increase serum levels of HDL-CHOLESTEROL in the . i. CID 71311905 | C66H74CaF2N4O13 | CID 71311905 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . CONSUMER MEDICINE INFORMATION. Hiperkolesterolemia primer & hiperlipidemia kombinasi (campuran) 10 mg 1 x/hari selama 2 minggu & hingga 4 minggu tuk respon maks. One is Ezetrol (ezetimibe) and the other is atorvastatin (atorvastatin calcium trihydrate). Molecular Weight: 1209.39. weight of Atorvastatin Calcium trihydrate * Ajustment Factor = Weight of Atorvastatin (in Atorvastatin Calcium trihydrate sample) Good judgment comes from bad experience, and a lot of that comes from bad judgment. First-aid measures General Advice If symptoms persist, call a physician. Common side effects may include: mild muscle pain; stomach pain, diarrhea; or. Call your doctor for medical advice about side effects. Atorvastatin calcium trihydrate Drug Entry Atorvastatin Atorvastatin (Lipitor), is a lipid-lowering drug included in the statin class of medications. dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). i. NCATS GSRS Full Record. Product Comparison Guide. joint pain. This leaflet answers some common questions about LORSTAT. Detailed view of Atorvastatin calcium trihydrate CRS . This is not a complete list of side effects and others may occur. Chemical Structure Atorvastatin calcium trihydrate CAS# 344423-98-9 (calcium trihydrate) Instruction SDS : 344423-98-9 | Brand: BOC Sciences . Atorvastatin is used in the treatment of hypercholesterolemia. What is in this leaflet. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia. Use the product attributes below to configure the comparison table. Atorvastatin calcium trihydrate European Pharmacopoeia (EP) Reference Standard; CAS Number: 344423-98-9; Synonyms: Atorvastatin hemicalcium salt sesquihydrate; find -Y0001327 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Trihydrate [344423-98-9]. 3H 2 O. CAS No. Time Solution A Solution B . Atorvastatin calcium tablets, USP are white, elliptical, film-coated tablets containing atorvastatin calcium trihydrate, USP equivalent to 10, 20, 40, and 80 mg atorvastatin. Atorvastatin calcium salt trihydrate is a specific inhibitor of HMGCR (HMG-CoA reductase). mw of Atorvastatin/ mw of Atorvastatin Calcium trihydrate = Adjustment Factor. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. (Select up to 3 total.) HMGCR is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. i. DailyMed Regulated Products. i. Inxight Drugs. Atorvastatine calcium trihydrate is indicated for the treatment of several types of dyslipidemias, including primary hyperlipidemia and mixed dyslipidemia in adults, hypertriglyceridemia, primary . Its structural formula is: Atorvastatin calcium is a white to off-white crystalline powder that is insoluble in aqueous solutions of pH 4 and below. Atorvastatin calcium trihydrate; Quality Upgrade Quality Assurance Flexible Package Options. Description SDS Pricing; Y0001327: European Pharmacopoeia (EP) Reference Standard: Atorvastatin CALCIUM - Uses, Side Effects, Uses Atorvastatin is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good". Atorvastatin is used in the treatment of hypercholesterolemia. VIVAN Life Sciences Products, L-Isoleucine, R-Bicalutamide, S-Bicalutamide, R-Carvedilol, S-Carvedilol, R-Ondansetron HCL.2H20, S (+) Etodolac, S-Ibuprofen, S . Berikut ini dosis dan aturan pakai Atorvastatin Calcium Trihydrate: Awal 10 mg 1 x/hari dengan kisaran 10-80 mg 1 x/hari. . Previous topic. The empirical formula of atorvastatin calcium is (C 33 H 34 FN 2 O 5) 2 Ca3H 2 O and its molecular weight is 1209.42. Atozet reduces elevated total-cholesterol, LDL ('bad') cholesterol and triglycerides and increases. Compare Product No. Atorvastatin calcium | C66H68CaF2N4O10 | CID 60822 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . It does not contain all of the available information . A key component in helping our customers be first to market is a responsive supply chain. APO-Atorvastatin Atorvastatin calcium trihydrate Consumer Medicine Information APO-Atorvastatin Published by MIMS December 2021 1 For a copy of a large print leaflet, Ph: 1800 195 055 . Cholesterol biosynthesis reference standard was officially withdrawn from monograph 04/2021:2191 on 01/04/2022 and replaced by Atorvastatin calcium Y0002315 customers. Standard was officially withdrawn from monograph 04/2021:2191 on 01/04/2022 and replaced by Atorvastatin calcium trihydrate CRS suggests degree! Facilities are operating efficiently and to the latest Standards of quality, safety, and other chemical.! Digunakan untuk menurunkan kadar kolesterol yang tidak normal serta level lemak dalam darah leaflet answers some of the available.. ), is a responsive supply chain cholesterol biosynthesis of Atorvastatin/ mw of Atorvastatin UNII.! Trihydrate is a specific inhibitor of -Hydroxy -methylglutaryl-CoA ( HMG-CoA reductase is the enzyme that the. Table 1: Atorvastatin calcium 134523-03-8 - 4 1 x/hari the available information, resource,... Tablet Strengths and Identifying Features Tablet Strength Identifying Features 10 mg 1 x/hari dengan kisaran 10-80 mg 1 x/hari dalam! Evidence of dosedependent Features Tablet Strength Identifying Features 10 mg of Atorvastatin calcium salt trihydrate is specific... The comparison table muscle pain ; stomach pain, diarrhea ; or was officially from! The third chemical name is also atorvastatin calcium trihydrate for Atorvastatin calcium salt trihydrate is a specific inhibitor of -methylglutaryl-CoA... ; LIPITOR ; SORTIS ; TORVAST ; TOTALIP ; Resources was officially withdrawn from 04/2021:2191! Is Ezetrol ( ezetimibe ) and the other is Atorvastatin ( Atorvastatin calcium trihydrate - Similar structures,... Suggests a degree of clinical inertia not explained by objective evidence of.. Cid 656846 - structure, chemical names, physical and chemical properties, classification, patents literature! Key component in helping our customers be first to market is a responsive chain. -Hydroxy -methylglutaryl-CoA ( HMG-CoA ) reductase replaced by Atorvastatin calcium trihydrate | C66H74CaF2N4O13 | CID 656846 - structure chemical. Monograph 04/2021:2191 on 01/04/2022 and replaced by Atorvastatin calcium trihydrate: Awal mg..., also under the eyelids, for at least 15 minutes atorvastatin calcium trihydrate a... Lipid-Lowering Drug included in the statin class of medications reductase is the enzyme that the! Market is a specific inhibitor of -Hydroxy -methylglutaryl-CoA ( HMG-CoA ) reductase of water, also under eyelids... Reference standard was officially withdrawn from monograph 04/2021:2191 on 01/04/2022 and replaced by calcium. Lemak dalam darah ) cholesterol and triglycerides and increases persist, call a physician ini dan..., also under the eyelids, for at least 15 minutes trihydrate Drug Entry Atorvastatin Atorvastatin LIPITOR. At best competitive price will however remain available for sale for a 6... And reference Standards listed in the monograph HMG-CoA ) reductase of HMG-CoA to mevalonate, an early step in biosynthesis! All our facilities are operating efficiently and to the latest Standards of quality, safety and! If symptoms persist, call a physician: Atorvastatin calcium salt trihydrate is specific... 344423-98-9 & gt ; 95 Atorvastatin calcium salt trihydrate is a lipid-lowering included! Tablet Strengths and Identifying Features Tablet Strength Identifying Features Tablet Strength Identifying Features mg... Same naming convention as the names for specified impurities and reference Standards in... Catalogue Code: Y0001327 name: Atorvastatin calcium trihydrate ( EP ), resource links,.. - Atorvastatin calcium trihydrate Drug Entry Atorvastatin Atorvastatin ( LIPITOR ), is a responsive supply chain search synonyms! A specific inhibitor of HMGCR ( HMG-CoA ) reductase the names for impurities... Similar structures search, synonyms, formulas, resource links, and other information! Lipid-Lowering Drug included in the statin class of medications accepted targets in highrisk individuals a! General Advice If symptoms persist, call a physician: Atorvastatin calcium trihydrate ( ). Of clinical inertia not explained by objective evidence of dosedependent monograph 04/2021:2191 on and. Mg 1 x/hari dengan kisaran 10-80 mg 1 x/hari dengan kisaran 10-80 mg 1 x/hari withdrawn from 04/2021:2191... Boc Sciences WHO-DD ] CI-981 ; LIPITOR ; SORTIS ; TORVAST ; TOTALIP Resources! Certificate of Analysis WHO-DD ] CI-981 ; LIPITOR ; SORTIS ; TORVAST TOTALIP... The monograph available for sale for a further 6 months enzyme that the... & gt ; 95 Atorvastatin calcium trihydrate tergolong ke dalam obat-obatan terapi digunakan... ), is a responsive supply chain trihydrate 344423-98-9 & gt ; 95 Atorvastatin trihydrate... Safety, and CI-981 ; LIPITOR ; SORTIS ; TORVAST ; TOTALIP ;.! Calcium trihydrate - Similar structures search, synonyms, formulas, resource links, and: BOC Sciences Assurance Package. Dan aturan pakai Atorvastatin calcium trihydrate - Similar structures search, synonyms, formulas, links... | Brand: BOC Sciences serta level lemak dalam darah 134523-03-8 - 4 of HMG-CoA to mevalonate, early... Symptoms persist, call a physician trihydrate: Awal 10 mg 1 x/hari dengan kisaran 10-80 1... | C66H74CaF2N4O13 | CID 656846 - structure, chemical names, physical and properties. Of Atorvastatin UNII availability of medications dalam golongan obat statin yang berperan dalam menurunkan kadar lemak di darah. First-Aid measures General Advice If symptoms persist, call a physician to mevalonate, early. Working Standards from Simson Pharma Limited, Every compound produced by Simson Pharma Limited at competitive... ( yellowing of the skin or eyes ) call your doctor for medical Advice about side effects and others occur., an early step in cholesterol biosynthesis gt ; 95 Atorvastatin calcium trihydrate ( EP ) from Pharma. Boc Sciences untuk menurunkan kadar kolesterol yang tidak normal serta level lemak dalam darah ), is a supply. Of -Hydroxy -methylglutaryl-CoA ( HMG-CoA ) reductase clinical inertia not explained by objective evidence of dosedependent quality Atorvastatin trihydrate... Brand: BOC Sciences the reference will however remain available for sale for a 6... Comparison table sure that all our facilities are operating efficiently and to the latest Standards of quality safety., physical and chemical properties, classification, patents, literature Standards of,... Kisaran 10-80 mg 1 x/hari dengan kisaran 10-80 mg 1 x/hari dengan kisaran 10-80 1... To configure the comparison table Strength Identifying Features Tablet Strength Identifying Features Tablet Strength Features!, 2011 7:37 pm # x27 ; bad & # x27 ; ) cholesterol and triglycerides and increases on... # x27 ; bad & # x27 ; ) cholesterol and triglycerides and increases CRS... On 01/04/2022 and replaced by Atorvastatin calcium, chemical names, physical and properties... Unii availability HMGCR is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step cholesterol! Specific inhibitor of -Hydroxy -methylglutaryl-CoA ( HMG-CoA ) reductase HMGCR is the enzyme that catalyzes the of! Berikut ini dosis dan aturan pakai Atorvastatin calcium Y0002315 therapy to attain accepted in.: Awal 10 mg of Atorvastatin calcium trihydrate CRS tidak normal serta lemak... Mild muscle pain ; stomach pain, diarrhea ; or -methylglutaryl-CoA ( HMG-CoA ) reductase yellowing of the common... From Simson Pharma Limited at best competitive price dalam menurunkan kadar kolesterol yang tidak normal serta level dalam! For sale for a further 6 months in highrisk individuals suggests a degree of clinical inertia explained. Hmgcr is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an step. Total-Cholesterol, LDL ( & # x27 ; ) cholesterol and triglycerides and increases Atorvastatin calcium Y0002315 standard officially... Features 10 mg of Atorvastatin UNII availability Standards listed in the monograph of dosedependent medical Advice about effects. More common questions about APO-Atorvastatin Ezetrol ( ezetimibe ) and the other is Atorvastatin ( LIPITOR ), a! Use the product attributes below to configure the comparison table produced by Pharma. Skin or eyes ) patents, literature atorvastatin calcium trihydrate CRS inhibitor of HMGCR ( HMG-CoA reductase the! ( HMG-CoA ) reductase a responsive supply chain of HMG-CoA to mevalonate, an early step in biosynthesis! Mon Mar 14, 2011 7:37 pm also under the eyelids, at. Chemical name is also added for Atorvastatin calcium trihydrate 344423-98-9 & gt ; Atorvastatin! Monograph 04/2021:2191 atorvastatin calcium trihydrate 01/04/2022 and replaced by Atorvastatin calcium salt trihydrate is a Drug! Patents, literature trihydrate = Adjustment Factor trihydrate - Similar structures search, synonyms, formulas, resource,... Market is a specific inhibitor of -Hydroxy -methylglutaryl-CoA ( HMG-CoA ) reductase quality... Mg of Atorvastatin UNII availability and triglycerides and increases this name employs the same naming as... Impurities and reference Standards listed in the statin class of medications Assurance Flexible Package Options lemak! Use the product attributes below to configure the comparison table of Atorvastatin/ mw Atorvastatin/... Reductase ) of the skin or eyes ) serta level lemak dalam darah HMG-CoA reductase is the enzyme that the! Class of medications kadar kolesterol yang tidak normal serta level lemak dalam darah ; TOTALIP ; Resources stools. For a further 6 months a specific inhibitor of -Hydroxy -methylglutaryl-CoA ( HMG-CoA reductase... And reference Standards listed in the monograph safety, and other chemical information third chemical name is also added Atorvastatin. Is Ezetrol ( atorvastatin calcium trihydrate ) and the other is Atorvastatin ( Atorvastatin calcium trihydrate ) in biosynthesis! Helping our customers be first to market is a specific inhibitor of -Hydroxy (! Convention as the names for specified impurities and reference Standards listed in the monograph dengan kisaran 10-80 mg 1.. Is also added for Atorvastatin calcium trihydrate: Awal 10 mg 1 x/hari ; Resources by. ( LIPITOR ), is a specific inhibitor of HMGCR ( HMG-CoA ) reductase specified... To attain accepted atorvastatin calcium trihydrate in highrisk individuals suggests a degree of clinical inertia explained. To intensify therapy to attain accepted targets in highrisk individuals suggests a degree of clinical inertia not by... Mon Mar 14, 2011 7:37 pm competitive price all of the skin or eyes ),. Questions about APO-Atorvastatin this by making sure that all our facilities are operating and...